Controlling Capillary Flow Rate on Lateral Flow Test Substrates by Tape

Rapid Lateral Flow Test Strips

Multiplex lateral-flow test strips fabricated by two-dimensional shaping.

We have fabricated paper- and nitrocellulose-based lateral-flow devices that are shaped in two dimensions by a computer-controlled knife. The resulting star, candelabra, and other structures are spotted with multiple bioassay reagents to produce multiplex lateral-flow assays. We have also fabricated laminar composites in which porous nitrocellulose media are sandwiched between vinyl and polyest...

Flow Rate Control in Pressure- Programmed Capillary Supercritical Fluid Chromatography

A versatile and simple system is described that allows variation of the column flow rate in open-tubular capillary supercritical fluid chromatography using both on-column and postcolumn detection. The system is based on column-effluent splitting in a low-dead-volume T piece at the column exit just before detection. The flow is split into two streams. One stream is fed to a flame ionization dete...

Cooperative Suction by Vertical Capillary Array Pump for Controlling Flow Profiles of Microfluidic Sensor Chips

A passive pump consisting of integrated vertical capillaries has been developed for a microfluidic chip as an useful component with an excellent flow volume and flow rate. A fluidic chip built into a passive pump was used by connecting the bottoms of all the capillaries to a top surface consisting of a thin layer channel in the microfluidic chip where the thin layer channel depth was smaller th...

False-negative result for cocaine metabolites on a lateral-flow drug test slide corrected by dilution.

To the Editor: Cocaine is one of the most widespread drugs of abuse; therefore, clinical laboratories are frequently requested to screen for the presence of cocaine and its metabolites in urine. When screening a urine specimen from a potential study participant for drugs of abuse, using a Verdict II lateral flow test slide (MEDTOX Diagnostics), multiple technologists obtained a negative screeni...